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Prof. Dr. Ruth Horn

Deputy Director, Akademische Oberr?tin
Ethics of Medicine
Phone: 0821 598 71008
Email:
Room: 04-EG.A012 (Faculty of Medicine / Gutenbergstra?e 7)
Address: Gutenbergstra?e 7, 86356 Neus??
Postal address: Universit?tsstra?e 2, 86159 Augsburg

Ruth works on ethical questions raised by medical practices and new technologies at the beginning and end of life in different socio-cultural contexts. Her research is at the intersection between sociology, bioethics and law/social policy. She has developed a comparative empirical bioethics approach to understand how ethical problems arise and are addressed in clinical settings where ethically sensitive decisions are made. Her approach combines literature review (e.g. professional literature, legal texts, professional guidelines, daily media), concept analysis (e.g. autonomy, dignity, empathy, solidarity in different socio-cultural contexts) and ethnographic research (interviews, observations, focus group discussions).

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Beginning of Life

Ruth's current research focuses on ethical issues arising from the clinical implementation of genomics in antenatal care. She is leading an? ESRC-funded project?exploring the ethical questions raised by the introduction of non-invasive prenatal testing (NIPT) into routine antenatal care in England, France and Germany. Previously, she has done research on the ethics of the prenatal assessment of genomes and exomes as part of the UK-wide? PAGE project.?

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Genomics

Ruth is co-lead and founder (with Marie Gaille, CNRS) of? UK-FR GENE?(UK-France Genomics and Ethics Network), a network for British and French researchers, policy-makers and?practitioners?to reflect on the ethical questions arising from the clinical applications of genomic technologies in each national context. If you are interested in our network, please get in touch!

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End of Life

In her previous research, Ruth has examined ethical questions at the end of life (e.g. assisted dying, continuous deep sedation, advance directives) with a particular focus on the tensions between patient autonomy and physicians' responsibility to protect life.

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Covid-19

Ruth is country team leader of the French study ' COVID-19: Comment cela vous affecte-t-il?' which is part of a multinational project on 'Solidarity in times of pandemics', led by Professor Barbara Prainsack at the University of Vienna.

Ruth Horn is professor of medical ethics and deputy director of the IEHHS, University of Augsburg and associate professor of ethics at the University of Oxford. She studied sociology at the Ludwig-Maximilians University, Munich, and the University of Paris Diderot. In 2009, she completed her PhD in Sociology of Ethics at the Ecole des Hautes Etudes en Sciences Sociales, Paris. From 2010 to 2013, she was a Marie Curie Fellow at the Centre for Ethics in Medicine, University of Bristol. Since 2013, Ruth has been a member of the? Ethox Centre, University of Oxford. In 2021, she joined the IEHHS, University of Augsburg. Ruth is also an associate member of the? SPHERE?research centre, CNRS, University of Paris Diderot.

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Ruth is regularly engaging with and contributing to the development of policy:

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Inter-/National level

2022: Ethical Guidance of the UK Joint Committee on Genomics in Medicine (R. Horn, A. Lucassen, A. Hall): ''. Royal College of Physicians, Royal College of Pathologists, and British Society of Genetic Medicine.

2020: Contributor to Written evidence from the Wellcome Centre for Ethics and Humanities (COV0156) into The Government¡¯s response to COVID-19: human rights implications. 2020: https://committees.parliament.uk/writtenevidence/8681/html/

2019-2020:?Chair of the British Society of Genetic Medicine (BSGM) working group on ¡®prenatal, preconception, pre-implantation genetic testing/diagnosis¡¯, BSGM Ethics and Policy Committee.

2019: Review of the Royal College of Obstetricians and Gynaecologists¡¯ Scientific Impact Paper on ¡®Evidence to Support the Clinical Utility of Prenatal Exome Sequencing in Evaluation of the Fetus with Congenital Malformations¡¯.

2018:?Review of Briefing Note ¡®Whole genome sequencing of babies¡¯,?Nuffield Council of Bioethics.

2018: Policy-consultation with the French ¡®General Inspectorate of Social Affaires¡¯ (Inspection General des Affaires Sociales, IGAS), to inform report ¡®?valuation du plan national 2015-2018 pour le d¨¦veloppement des soins palliatifs et l¡¯accompagnement en fin de vie¡¯ (eds.?N. Bohic, F. Fellinger, M. Sa?e and L-C. Viossat), telephone interview with L.-C. Viossat, 23.01.2018.?

2017: Advisory group on ¡®Advance Directives¡° of the French National Centre of Palliative Care and the End of Life (Centre National des Soins Palliatifs et de la Fin de Vie), Paris, resulting in the report (eds.?I. Marin, S. Bretonniere) ¡®Un an de politique active en faveur des directives anticip¨¦es. Quels progr¨¨s, quelles limites, quelles pistes pour l¡¯avenir ?¡¯, 2018.

2014: Policy-consultation with the Parliamentary Mission of Information on ¡°End of Life¡±, organised by J. Leonetti and A. Claeys, French National Assembly, Paris, 08.10.2014.?The resulting report informed the 2016 law on the end-of-life ¡®Loi 2016-87 du 2 f¨¦vrier 2016 cr¨¦ant de nouveaux droits en faveur des malades et des personnes en fin de vie. Journal Officiel 2016.?0028¡¯.

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Local level

2020: ¡®Guidance for research in response to humanitarian emergencies¡¯,?CUREC, University of Oxford

2020:?¡®Data Handling Scoping¡¯ (workshop),?CUREC, University of Oxford

2019: ¡®Empirical studies involving qualitative research methods¡¯ (OxTREC application?guide)

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Awards

2024: Adjunct Professor of Medical Ethics, University of Augsburg

2020: Associate Professor in Ethics, Medical Sciences Division, University of Oxford

2015: University Research Lecturer, Medical Sciences Division, University of Oxford?

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Research grants/ PI

2023: Deutsche Forschungsgesellschaft, Middle East Cooperation,?HO 7477/1-1, PI, Co-PI: Prof. Aviad Raz, Ben Gurion University, IL, Project title: 'Genetic testing and/or screening for cystic fibrosis in Israel and Germany: The interplay of policies and socio-ethical considerations', €432.424.

2020:?Economic and Social Research Council, Research Grant,?ES/T00908X/1, Project title: ¡®Non-invasive prenatal genetics and genomics in England, France and Germany - Exploring practical ethical issues 'on the ground'¡¯, ?908.340.

2020:?Medical Division COVID-19 Research Response Fund, British Academy Special Research Grants: Covid-19, Co-I, Project title: ¡®COVID-19: Comment cela vous affecte-t-il?, Une ¨¦tude qualitative comparative et longitudinale¡¯, country lead for French study arm of multinational project: ¡®Solidarity in times of a pandemic: What do people do, and why?, led by Prof. B. Prainsack, University of Vienna, ?19.250.

2020: NDPH Pump Priming Award, Nuffield Department of Population Health, University of Oxford, Co-I, to investigate the ethics of ¡®Synthetic Cohort Studies and Biobank¡¯, ?28.590.

2013 ¨C 2016: Ethics and Society Research Fellowship, 100553/Z/12/7, Wellcome Trust, PI, Project title: Between patient autonomy and physicians¡¯ responsibility to save life: The implementation of advance directives in three European countries (England, France, and Germany), ?173.658.

2010 ¨C 2012: Marie Curie Intra-European Fellowship, ADVANCED-FP7-PEOPLE-2009-IEF-254825,?European?Commission, PI, Project title: Advance directives in England and France, €171.741.

2010-2012: Post-doctoral Grant,?Ligue Nationale Contre le Cancer, PI, €70.000.

2005 ¨C 2009: PhD Grant,?Caisse Nationale d¡¯Assurance Maladie des Travailleurs Salari¨¦s?(CNAMTS), PI, €60.000.

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Small grants

2020: Seed-Meeting Grant, Co-I, Higher Education, Research and Innovation Department, Embassy of France, London, workshop entitled ¡®UK-FR GENE (Genomics and Ethic Network)¡¯, October 2020, ?6000.

2019: Big Data Institute Workshop Grant, University of Oxford, PI, to contribute to a French-UK workshop entitled ¡®Comparative Perspectives on Ethical, Legal and Social Issues of Genomics in Research and Practice¡¯, ?7800.

2019: French Embassy Workshop Grant, Co-I, Higher Education, Research and Innovation Department, Embassy of France, London, to contribute to a French-UK workshop entitled ¡®Comparative Perspectives on Ethical, Legal and Social Issues of Genomics in Research and Practice¡¯, €2500.

2014 ¨C 2018: Junior Research Fellowship, Linacre College, Oxford, ?300 per annum.

2014: Society and Ethics Small Grant, Wellcome Trust, PI, to organise a workshop entitled ¡®Autonomy and Solidarity two conflicting values in bioethics? British and French perspectives on two core values in health care and medicine¡¯, ?3.070.

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Visiting fellowships

Sept/Oct 2020: Guest researcher of the DEA Programme (Directeurs d¡¯?tudes Associ¨¦s, or Associate Research Directors), Fondation Maison des Sciences de l¡¯Homme and French Secretary of State for Universities, Paris, €3400.

October 2017: Brocher Foundation Residency Fellowship?

Project: Prenatal whole genome/exome sequencing and professional responsibilities in shaping public healthcare provision.?

March 2017: Guest Professorship, University Paris 7, Paris Diderot, SPH¨¨re

Project: Ethical issues of prenatal whole genome sequencing €3800.

Nov/Dec 2012:?International Visiting Fellowship in Medical Ethics, Institute for Medical Ethics and History of Medicine, Ruhr-University, Bochum (GER)

Project: Advance directives in England, France and Germany, ?4000.

May 2012:Visiting Scholar, Hastings Center (NY, USA)

Project: Ethical and economic aspects of advance directives

April 2012: Visiting Scholarship Caroline Miles, The Ethox

Project: Legal and ethical issues of advance directives ?2000.

Since 2022 Member of the scientific advisory boards of the German Human Genome-Phenome Archive

Since 2021 Member of the CNRS Ethics Committee ( COMETS)

Since 2021 Member of the UK? Fetal Genomics Group?der British Society for Genetic Medicine.

Since 2020 President of the? European Association of Centres of Medical Ethics?(EACME).?

Since 2020 Chair of the working group ¡®Prenatal Genetic Testing¡¯ of the? British Society for Genetic Medicine.

Since 2018 Co-lead and funder of? UK-FR GENE?(UK-France Genomics and Ethics Network)

Since 2018 Member of Oxford Tropical Research Ethics Committees?(OxTREC).

2018-2020 Co-lead of the discussion group ¡®Ethics und AI¡¯, Big Data Institute Film Discussion Group, University of Oxford.

2018-2020 Secretaire General of the EACME.

2016-2018 Treasurer of the EACME.

2017 Member of the advisory group on ¡®Advance Directives¡° of the French National Centre of Palliative Care and the End of Life (Centre National des Soins Palliatifs et de la Fin de Vie), Paris, resulting in the report (eds. I. Marin, S. Bretonniere) ¡®Un an de politique active en faveur des directives anticip¨¦es. Quels progr¨¨s, quelles limites, quelles pistes pour l¡¯avenir ?¡¯, 2018.

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Publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2011 | 2010 | 2009 | 2006

2024

Bernardi Christine, Wolff Daniel, L¨¹ke Florian, Hies Johannes, Hallowell Nina, Horn Ruth, Seitz Frederike, Heudobler Daniel, Hermann-Johns Anne. "Uninformed consent" in clinical trials with cancer patients: a qualitative analysis of patients' and support persons' communication experiences and needs. https://doi.org/10.1016/j.pec.2024.108144
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Horn Ruth, Merchant Jennifer. Ethical and social implications of public¨Cprivate partnerships in the context of genomic/big health data collection. https://doi.org/10.1038/s41431-024-01608-9
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For a full list of the UK-FR+GENE (Genetics and Ethics Network) Consortium please visit the website: https://doi.org/10.1038/s41431-024-01608-9
Horn Ruth, Hall Alison, Lucassen Anneke. Ethical considerations in prenatal genomic testing. https://doi.org/10.1016/j.bpobgyn.2024.102548
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Nov-Klaiman Tamar, Bowman-Smart Hilary, Horn Ruth. Negotiating severity behind the scenes: prenatal testing in Germany. https://doi.org/10.1038/s41431-024-01612-z
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Bowman-Smart Hilary, Perrot Adeline, Horn Ruth. Supporting patient decision-making in non-invasive prenatal testing: a comparative study of professional values and practices in England and France. https://doi.org/10.1186/s12910-024-01032-0
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2023

Horn Ruth, Merchant Jennifer, Abecassis Marion, Bale Mark, Chneiweiss Herv¨¦, Hallowell Nina, Kerasidou Angeliki, Lucassen Anneke, Montgomery Jonathan, Parker Michael, Patch Christine, Winkler Eva. Managing expectations, rights, and duties in large-scale genomics initiatives: a European comparison. https://doi.org/10.1038/s41431-022-01247-y
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Author list: Ruth Horn, Jennifer Merchant & The UK-FR GENE Consortium
Bowman-Smart Hilary, Wiesemann Claudia, Horn Ruth. Non-invasive prenatal testing in Germany: a unique ethical and policy landscape. https://doi.org/10.1038/s41431-022-01256-x
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Boardman Felicity, Horn Ruth. Not putting the cart before the horse: the complex social and ethical terrain of prenatal exome sequencing. https://doi.org/10.1038/s41431-022-01225-4
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Raz Aviad, Minari Jusaku, Takashima Kayo, Gaydarska Hristina, Hashiloni-Dolev Yael, Horn Ruth. Old and new challenges regarding comparable and viable data sharing in population-scale genomic research. https://doi.org/10.1038/s41431-023-01355-3
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Perrot Adeline, Horn Ruth. Preserving women's reproductive autonomy while promoting the rights of people with disabilities? The case of Heidi Crowter and Maire Lea-Wilson in the light of NIPT debates in England, France and Germany. https://doi.org/10.1136/medethics-2021-107912
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Kieslich Katharina, Fiske Amelia, Gaille Marie, Galasso Ilaria, Geiger Susi, Hangel Nora, Horn Ruth, Lanzing Marjolein, Libert S¨¦bastien, Lievevrouw Elisa, Lucivero Federica, Marelli Luca, Prainsack Barbara, Sch?nweitz Franziska, Sharon Tamar, Spahl Wanda, Van Hoyweghen Ine, Zimmermann Bettina M.. Solidarity during the COVID-19 pandemic: evidence from a nine-country interview study in Europe. https://doi.org/10.1136/medhum-2022-012536
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Perrot Adeline, Clarke Angus, Vassy Carine, Horn Ruth. Women's preferences for NIPT as a first©\line test in England and France: challenges for genetic counseling practices. https://doi.org/10.1002/jgc4.1839
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2022

Zimmermann Bettina M., Wagenaar Hendrik, Kieslich Katharina, Prainsack Barbara, Meyers Gert, Buyx Alena, El-Sayed Seliem, Fiske Amelia, Galasso Ilaria, Geiger Susi, Hangel Nora, Horn Ruth, Johnson Stephanie, Kuiper Janneke M.L., Lucivero Federica, McLennan Stuart, Paul Katharina T., Pot Mirjam, Radhuber Isabella, Samuel Gabrielle, Sharon Tamar, Siffels Lotje, Van Hoyweghen Ine, Awad Sula, Bourgeron Th¨¦o, Eichinger Johanna, Gaille Marie, Haddad Christian, Hayes Sarah, Hoffman Andrew, Jasser Marie, Kenens Joke, Lanzing Marjolein, Libert S¨¦bastien, Lievevrouw Elisa, Marelli Luca, Ongolly Fernandos, Phillips Amicia, Pinel Cl¨¦mence, Riesinger Katharina, Roberts Stephen, Saxinger Gertrude, Schlogl Lukas, Sch?nweitz Franziska, Sierawska Anna, Spahl Wanda, Stendahl Emma, Vanstreels Siemen, Vidolov Simeon, Weiss Elias. Democratic research: setting up a research commons for a qualitative, comparative, longitudinal interview study during the COVID-19 pandemic. https://doi.org/10.1016/j.ssmqr.2022.100158
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Perrot Adeline, Horn Ruth. Health professionals and scientists¡¯ views on genome-wide NIPT in the French public health system: critical analysis of the ethical issues raised by prenatal genomics. https://doi.org/10.1371/journal.pone.0277010
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Horn Ruth. NIPT and the concerns regarding 'routinisation'. https://doi.org/10.1038/s41431-022-01053-6
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Lucivero Federica, Marelli Luca, Hangel Nora, Zimmermann Bettina Maria, Prainsack Barbara, Galasso Ilaria, Horn Ruth, Kieslich Katharina, Lanzing Marjolein, Lievevrouw Elisa, Ongolly Fernandos, Samuel Gabrielle, Sharon Tamar, Siffels Lotje, Stendahl Emma, Van Hoyweghen Ine. Normative positions towards COVID-19 contact-tracing apps: findings from a large-scale qualitative study in nine European countries. https://doi.org/10.1080/09581596.2021.1925634
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Perrot Adeline, Horn Ruth. The ethical landscape(s) of non-invasive prenatal testing in England, France and Germany: findings from a comparative literature review. https://doi.org/10.1038/s41431-021-00970-2
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2021

Lewis Celine, Buchanan James, Clarke Angus, Clement Emma, Friedrich Bettina, Hastings-Ward Jillian, Hill Melissa, Horn Ruth, Lucassen Anneke M., Patch Chris, Pickard Alexandra, Roberts Lauren, Sanderson Saskia C., Wynn Sarah L., Vindrola-Padros Cecilia, Lakhanpaul Monica. Mixed-methods evaluation of the NHS Genomic Medicine Service for paediatric rare diseases: study protocol. https://doi.org/10.3310/nihropenres.13236.1
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Ye Ziqing, Hu Wenhui, Wu Bingbing, Zhang Yueping, Lei Caixia, Williams Isabelle, Shouval Dror S., Kanegane Hirokazu, Kim Kyung Mo, de Ridder Lissy, Shah Neil, Ling Galina, Yerushalmi Baruch, Kotlarz Daniel, Snapper Scott, Horn Ruth, Klein Christoph, Muise Aleixo M., Huang Ying, Uhlig Holm H.. Predictive prenatal diagnosis for infantile-onset inflammatory bowel disease because of interleukin-10 signalling defects. https://doi.org/10.1097/mpg.0000000000002937
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Gaille Marie, Horn Ruth. The ethics of genomic medicine: redefining values and norms in the UK and France. https://doi.org/10.1038/s41431-020-00798-2
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2020

Pfeifer Ulrich, Horn Ruth. Can there be wrongful life at the end of life? German courts revisit an old problem in a new context. https://doi.org/10.1136/medethics-2019-105883
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Horn Ruth. Law, public debates and professionals¡¯ attitudes: a comparative study on the use of advance directives in England, France and Germany. https://doi.org/10.1007/978-3-030-40033-0_18
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Horn Ruth, Kerasidou Angeliki. Sharing whilst caring: solidarity and public trust in a data-driven healthcare system. https://doi.org/10.1186/s12910-020-00553-8
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Horn Ruth. The right to a self-determined death as expression of the right to freedom of personal development: the German Constitutional Court takes a clear stand on assisted suicide. https://doi.org/10.1136/medethics-2020-106197
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2019

Horn Ruth. La France et la Grande-Bretagne ¨¤ l¡¯¨¨re de la m¨¦decine g¨¦nomique: nouveaux d¨¦fis ¨¦thiques en m¨¦decine de la reproduction. https://doi.org/10.1051/medsci/2019004
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2018

Kerasidou Angeliki, Horn Ruth. Empathy in healthcare: the limits and scope of empathy in public and private systems. https://doi.org/10.4324/9781315186351
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Horn Ruth, Parker Michael. Health professionals' and researchers' perspectives on prenatal whole genome and exome sequencing: 'we can't shut the door now, the genie's out, we need to refine it'. https://doi.org/10.1371/journal.pone.0204158
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2017

Horn Ruth, Parker Michael. Opening Pandora's box? Ethical issues in prenatal whole genome and exome sequencing. https://doi.org/10.1002/pd.5114
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Horn Ruth. The ¡®French exception¡¯: the right to continuous deep sedation at the end of life. https://doi.org/10.1136/medethics-2017-104484
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Horn Ruth. ¡°Why should I question a patient¡¯s wish?¡±: a comparative study on physicians¡¯ perspectives on their duties to respect advance directives. https://doi.org/10.1163/15718093-12341437
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2016

Kerasidou Angeliki, Horn Ruth. Making space for empathy: supporting doctors in the emotional labour of clinical care. https://doi.org/10.1186/s12910-016-0091-7
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Gaille Marie, Horn Ruth. Solidarity and autonomy: two conflicting values in English and French health care and bioethics debates?. https://doi.org/10.1007/s11017-016-9391-7
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Horn Ruth, Kerasidou Angeliki. The concept of dignity and its use in end-of-life debates in England and France. https://doi.org/10.1017/s0963180116000050
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Gaille Marie, Horn Ruth. The role of ¡®accompagnement¡¯ in the end-of-life debate in France: from solidarity to autonomy. https://doi.org/10.1007/s11017-016-9389-1
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2015

Horn Ruth. Physicians¡¯ perspectives on patient preferences and advance directives in England and France: other countries, other requirements?.
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2014

Horn Ruth. Advance directives in English and French law: different concepts, different values, different societies. https://doi.org/10.1007/s10728-012-0210-7
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Horn Ruth. ¡°I don¡¯t need my patients¡¯ opinion to withdraw treatment¡±: patient preferences at the end-of-life and physician attitudes towards advance directives in England and France. https://doi.org/10.1007/s11019-014-9558-9
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2013

Huxtable Richard, Horn Ruth. Continuous deep sedation at the end of life: balancing benefits and harms in England, Germany and France. https://doi.org/10.1017/cbo9781139856652.010
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Horn Ruth, Huxtable Richard, Jox R. J.. European perspectives on ethics and law in end-of-life care.
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Horn Ruth. Le droit de mourir: choisir sa fin de vie, en France et en Allemagne.
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Horn Ruth, ter Meulen Ruud. The use of advance directives in the context of limited resources for healthcare. https://doi.org/10.1007/978-94-007-7377-6_12
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2011

Horn Ruth. Euthanasia and end-of-life practices in France and Germany: a comparative study. https://doi.org/10.1007/s11019-011-9357-5
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2010

Horn Ruth. Die Sterbehilfe-Debatte in Deutschland und Frankreich: Gesellschaftsproblem und sozialer Sachverhalt. https://doi.org/10.1007/978-3-531-92259-1_6
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Horn Ruth. Le d¨¦bat sur l'euthanasie et ses r¨¦percussions sur les pratiques m¨¦dicales en fin de vie, un regard comparatif: France - Allemagne. https://doi.org/10.3917/pos.414.0323
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2009

Horn Ruth. L¡¯euthanasie en d¨¦bat: la prise en charge des malades en fin de vie (une comparaison entre l¡¯Allemagne et la France).
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Horn Ruth. Welche Art von Selbstbestimmung f¨¹r sterbenskranke Patienten? Eine vergleichende Studie in Frankreich und Deutschland.
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2006

Horn Ruth, Saake Irmhild, Roser Traugott. Ein ?berblick ¨¹ber den Verlauf der Sterbehilfe-Debatte in Frankreich.
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